| Contents: Volume 1, Nomber 2; Jan, 2003
 | 
         
          |  | 
         
          | Role 
              of Laryngeal Mask Airway in First Aids in Confined Space
 
 | 
         
          | Tzong-Luen Wang, MD, PhD, Kuo-Chih Chen, MD, Hsueh-Ju 
            Teng, MD, and Hang Chang, MD, PhD | 
         
          |  
                From the Department of Emergency Medicine(Wang 
                TL, Chen KC, Teng HJ, Chang H), Shin-Kong Wu Ho-Su Memorial Hospital. 
                  Correspondence to Dr. Hang Chang, Department 
                of Emergency Medicine, Shin-Kong Wu Ho-Su Memorial Hospital, 95 
                Wen Chang Road, Taipei, Taiwan. E-mail M001043@ms.skh.org.tw   | 
         
          |  Abstract
 | 
         
          |  |  | 
         
          | Laryngeal mask airway (LMA) has 
              been shown to be an alterative method of definite airway but its 
              role in rescue from confined space has not been determined. One 
              hundred and sixty seven persons who attended the training course 
              of disaster medicine were enrolled as the study population. Sixty 
              two of them were men whereas the other 105 women. Thirty four of 
              the study population were medical doctors, 95 nurses, 30 emergency 
              medical technicians, and 8 laypersons. We arranged a workshop of 
              confined space medicine. The comparison of applicability between 
              conventional endotracheal intubation and LMA was made. Before evaluation, 
              every participant accepted detailed illustration and demonstration 
              of the skills. Every one was asked to perform airway management 
              for the manikins in confined space with face down, sitting position, 
              side position and “reverse” supine position. The success rate and 
              the time elapse for both endotracheal intubation and LMA application/intubation 
              was compared. Success rate of first LMA application is 100% for 
              all positions which is significantly better than those of endotracheal 
              intubation (85% for sitting position, P<0.01; 80% for side position, 
              P<0.01; 76% for face down, P<0.01; and 74% for “reverse” supine 
              position, P<0.001). The time elapse for first LMA application 
              was also significantly lower than those of endotracheal intubation 
              (as presented). The success rate and time elapse of first LMA intubation 
              and the number of trials before success was comparable to endotracheal 
              intubation. LMA was preferred as a choice of airway management in 
              confined space rescue. (Ann Disaster Med. 2003;1:85-96)Key words: Laryngeal Mask Airway; Confined Space; First Aid; Disaster
 | 
         
          | 
 |  | 
         
          |  Introduction
 |  | 
         
          |  |  | 
         
          | Although there have been many advances 
              in first aids in recent decades, the rescue in confined space still 
              remained a great challenge. For example, it may be difficult for 
              the rescue team or disaster medical assistant team (DMAT) to maintain 
              airway in a narrow space with no good preparation. The laryngeal 
              mask airway (LMA) may be a resolution under such circumstances. 
              The LMA was designed in the 1980’s and has gained widespread popularity 
              in clinical use in the last decade.1,2  
              It allows either spontaneous or positive-pressure ventilation. With 
              advances in the design, it has also received more attention as a 
              tool for management of the difficult airway.3-5  
              Because the placement of this device is less technique-dependent, 
              the learning curve will be adequate.6-10  
              In other words, the LMA has theoretical basis for the rescue team 
              or DMAT to learn and use under difficult situations.10-14  
              We then underwent the following study to compare the efficiencies 
              between traditional intubation and the LMA with or without intubation 
              in the confined space.  | 
         
          |  |  | 
         
          |  Methods | 
         
          |  |  | 
         
          |  Study population  | 
         
          | One hundred and sixty seven persons 
              who attended the training course of disaster medicine in 2001 were 
              enrolled as the study population. Sixty two of them were men whereas 
              the other 105 women. Thirty four of the study population were medical 
              doctors, 95 nurses, 30 emergency medical technicians, and 8 laypersons. 
              According to the education background, 147 of them (88%) have ever 
              qualified as the basic life science providers, 70 (42%) as the providers 
              of advanced cardiovascular life support, and 55 of them (12%) were 
              neither. We therein classified the students into 4 classes according 
              to their self-determination in performance of intubation: Class 
              A (n=30), those who had good clinical experiences in intubation; 
              Class B (n=18) who ever completed the training of intubation but 
              had only limited clinical experiences; Class C (n=99) who had ever 
              attended the training course of intubation with no real performance; 
              and Class D (n=55) that had never been trained. | 
         
          |  |  | 
         
          | Study protocol | 
         
          | We arranged a workshop of confined space medicine to 
            compare the applicability between conventional endotracheal intubation 
            and LMA with and without intubation. Before evaluation, every participant 
            accepted detailed illustration and demonstration of the skills. Every 
            one was asked to perform airway management for the manikins in confined 
            space with the following four positions: face down, sitting position, 
            side position and “reverse” supine position. The students would be 
            asked to re-prepare and intubate if initial attempts failed. The success 
            rate and the time elapse for both endotracheal intubation and LMA 
            application/intubation was compared. | 
         
          |  | 
         
          | Statistic Analysis | 
         
          | The categorical data were inputted in Microsoft Excel 
            2000 for descriptive statistics and further qualitative analysis. 
            These results were analyzed using the chi-squared test. ANOVA with 
            a Newman-Keuls post hoc test was used to determine whether any significant 
            differences existed among continuous data. A P<0.05 was considered 
            to be statistically significant. | 
         
          |  | 
         
          |  |  | 
         
          |  Results |  | 
         
          |  |  | 
         
          | For all positions, the success 
              rate of first LMA application is 100% and significantly better than 
              those of endotracheal intubation (85% for sitting position, P<0.01; 
              80% for side position, P<0.01; 76% for face down, P<0.01; 
              and 74% for “reverse” supine position, P<0.001) (Figure 1  ). 
              The time elapse for first successful LMA application was also significantly 
              lower than those of endotracheal intubation (Figure 2A  ). 
              The success rate of first LMA intubation was comparable to that 
              of endotracheal intubation (88% vs. 85% for sitting position, P=NS; 
              80% vs. 80% for side position, P=NS; 78% vs. 76% for face down, 
              P=NS; and 76% vs. 74% for “reverse” supine position, P=NS) (Figure 
              3  ), 
              as was the time elapse between two comparisons (Figure 2B  ). 
              The number of trials before successful application of endotracheal 
              tube was also comparable between two methods (data not shown). 
              To elucidate the possible effects of past experiences, we analyzed 
              the learning results according to the classification described above. 
              There were no differences in applying LMA and LMA intubation among 
              4 groups of different past experiences (for example, 88% for Class 
              A, 84% for Class B, 85% for Class C, and 72% for Class D in LMA 
              intubation, Figure 4A   and 
              4B  ) 
              whereas there were significant differences for conventional intubation 
              (96% for Class A, 80% for Class 64% for Class C, and 30% for Class 
              D in LMA intubation, P<0.001 among 4 groups) (Figure 4C  ). 
              The similar findings were also observed according to the performance 
              among different medical background. In other words, the success 
              rate were not significantly different in applying LMA or LMA intubation 
              no matter the students were physicians, nurses, emergency medical 
              technicians, or laypersons (Figure. 5  ). | 
         
          |  |  | 
         
          | 
               
                |  | Figure 1. The comparisons in success rate of first 
                  LMA application and conventional intubation |  |  | 
         
          |  | 
         
          |  |  | 
         
          | 
               
                |  | Figure 2. The comparisons in time relapse between 
                  LMA application and conventional intubation (A) and LMA intubation 
                  and conventional intubation (B) |  |  | 
         
          |  |  | 
         
          | 
               
                |  | Figure 3. The comparisons in success rate of first 
                  LMA intubation and conventional intubation |  |  | 
         
          |  |  | 
         
          | 
               
                |  | Figure 4. The comparisons in success rate of LMA 
                  application, LMA intubation and conventional intubation in groups 
                  of different experiences |  |  | 
         
          |  |  | 
         
          | 
               
                |  | Figure 5. The comparisons in success rate of LMA 
                  application, LMA intubation and conventional intubation in groups 
                  of different medical backgrounds |  |  | 
         
          |  |  | 
         
          |  |  | 
         
          |  Discussion |  | 
         
          |  |  | 
         
          | In prehospital situations, the 
              LMA and the Combitube dual-lumen tube are both time-saving procedure 
              for maintaining patent airways.9,10,15-17  
              However, in one study comparing the LMA and the Combitube for inexperienced 
              operators, the rate of successful LMA placements in anesthesized 
              and paralyzed patients was 100%, but the success rate only 92% with 
              a Combitube.10  More complicated procedures 
              may contribute to the failure of the Combitube. In addition, the 
              Combitube cannot be used in patients with a protective reflex or 
              in pediatric victims, whereas the LMA has no such limitations.18  
              Another study7  showed that physicians-in-training 
              could insert an LMA successfully in 90% of victims with cardiopulmonary 
              arrest even when they hadn’t had any clinical experience using an 
              LMA. 
              The above observations have been again proven in our investigations. 
              The success rate of LMA application was almost 100% for every student, 
              independent of their education background and experiences. Evidence 
              from some preliminary studies (including our data) revealed that 
              the application of the LMA is not affected by the patient position,19  
              past experience,7-9  consciousness level,1-4 or cervical immobilization.21-23  
              These characteristics make the LMA more attractive in rescue of 
              victims in confined spaces. Our data revealed that the success rate 
              of first LMA application was 100% for various patient positions, 
              which is significantly better than the rates for endotracheal intubation 
              (85% for the sitting position; 80% for side position; 76% for face 
              down; and 74% for “reverse” supine position). The time elapsed for 
              first LMA application was also significantly lower than that for 
              endotracheal intubation. The success rate and time elapsed for first 
              ILMA and the number of trials before success was comparable to endotracheal 
              intubation. The advantages of LMA over conventional intubation in 
              different positions have demonstrated that the pre-shaped design 
              in LMA has overcome many clinical difficulties in using laryngoscope 
              and preparations.  
              However, the success of LMA rescue in the clinical settings still 
              depends on several factors such as the operator’s experience, clinical 
              pathways in airway management, and understanding of the interaction 
              between LMA insertion and cricoid pressure.6  
              Surveys have demonstrated that the success rates in emergency rescue 
              are probably lower overall due to lack of familiarity with the device.7-10 The overall LMA insertion success rate was 81% in 233 cases 
              in an Australian prehospital study.11  
              Japanese paramedics’ experiences also showed overall excellent outcomes.12 Brimacombe et al.13,14  therein 
              suggested an algorithm for use of the LMA in failed intubation of 
              the nonfasting patient.  | 
         
          |  |  | 
         
          | LMA as a Conduit Passage |  | 
         
          | Although the ILMA may be not the 
              first priority for most pre-hospital and confined space rescues, 
              it is still worthwhile to understand the LMA’s role as a conduit 
              for passing an endotracheal tube. A newly designed ILMA was specifically 
              designed for intubation. The trachea may thus be intubated blindly 
              through a properly placed LMA.24  However, 
              success rates vary, depending on the operator’s experience,25  
              technique, number of attempts, and equipment26,27 according to others’ reports. With the advances in design modification, 
              the LMA may be used as a guide for a thin flexible airway stent 
              such as an elastic bougie or an intubating stylet for the passage 
              of an endotracheal tube.13,28-30  
              Retrograde tracheal intubation over a catheter through an LMA has 
              also been reported.31-36  Because of 
              technical difficulty in fibroptic intubation and retrograde tracheal 
              intubation for emergency physicians and being impractical in clinical 
              use, the usefulness in disaster medicine should be underscored. |  | 
         
          |  | 
         
          | Limitations of LMA | 
         
          | The primary concern with LMA use 
              by emergency physicians and paramedics is incomplete protection 
              of the airway. There is a risk of aspiration in prehospital use 
              of the LMA because the device does not separate the trachea and 
              esophagus completely.37-38  The Sellick 
              maneuver should be maintained continuously for high-risk patients, 
              such as those who have had bag ventilation and those in a non-fasting 
              state, in late pregnancy, with morbid obesity, or with upper gastrointestinal 
              hemorrhage. Although these were conflicting results in some reports,39,40  
              Brimacombe’s meta-analysis41  found 
              an incidence of 2 aspirations in 10,000 patients. We still need 
              to elucidate is whether aspiration is more commonly encountered 
              in the emergency department and prehospital situations because of 
              inadequate preparation. 
              Another problem is the use of the LMA in patients with either increased 
              airway resistance or very low lung compliance.18  
              Inadequate ventilation due to air leakage and gastric distension 
              are predictable in attempting positive ventilation in “tight” asthmatics. 
              The LMA, as in conventional intubation, may induce reflex bronchospasm. 
              However, the severity is always less because the diameter of the 
              LMA is larger and because the LMA does not pass through the trachea.18,42  Patients already in bronchospasm need to be monitored carefully.43  
              Other complications resulting from LMA use are local irritation 
              causing coughing and bucking, upper airway injuries, pressure-induced 
              lesions (such as twelfth cranial nerve palsy), and sometimes hemodynamic 
              compromise.44,45  Among them, pressure-induced 
              injuries may be related to an over-inflated cuff which causes mucosal 
              ischemia with subsequent injury.46-48  
              Adequate cuff pressure and proper insertion technique are the primary 
              prevention strategies. | 
         
          |  | 
         
          | Conclusion | 
         
          | The success rate and time elapse 
              of LMA application and first LMA intubation and the number of trials 
              before success were comparable to endotracheal intubation. LMA and 
              its intubation were preferred as a choice of airway management in 
              confined space rescue. | 
         
          |  |  | 
         
          |  References |  | 
         
          |  |  | 
         
          | 1. | 1. Brain AIJ. The laryngeal mask airway: a possible 
            new resolution to airway problems in the emergency situation. Arch 
            Emerg Med 1984;1:229-32 | 
         
          | 2. | 2. Brain AIJ. Historical aspects and future directions. In: Ferson 
            DZ, Brimacombe JR, Brain AIJ, eds. International airway clinics: the 
            Laryngeal Mask Airway. New York, Lincott-Williams and Wilkins Co. 
            1998;36:1-18 | 
         
          | 3. | 3. Caplan R, Benumof JL, Berry FA, et al. Practice guidelines for 
            management of the difficult airway: A report by the ASA Task Force 
            on management of the difficult airway. Anesthesiology 1993;78:597-602 | 
         
          | 4. | 4. Benumof J. Laryngeal mask airway and the ASA difficult airway 
            algorithm. Anesthesiology 1996;84:686-99 | 
         
          | 5. | 5. Airway and Ventilation Management Working Group of the European 
            Resuscitation Council. Guidelines for the advanced management of the 
            airway and ventilation during resuscitation. Resuscitation 1996;31:201-30 | 
         
          | 6. | 6. Brimacombe JR, Berry AM, Daves SM. The laryngeal mask airway. 
            In: Hanowell LH, Waldron RJ, eds. Airway management. Philadelphia, 
            PA: Lippincott-Raven Publishers; 1996:195-211 | 
         
          | 7. | 7. Kokkinis K. The use of the Laryngeal Mask Airway in CPR. Resuscitation 
            1994;27:9-12 | 
         
          | 8. | 8. Samarkandi AH, Seraj MA, El Dawlatly A, Mastan M, Bakhamees 
            HB. The role of the Laryngeal Mask Airway in cardiopulmonary resuscitation. 
            Resuscitation 1994;28:103-6 |  | 
         
          | 9. | 9. Davis PRF, Tighe SQM, Greenslade GL, et al. Laryngeal mask airway 
            and endotracheal tube insertion by unskilled personnel. Lancet 1990;336:977-9 |  | 
         
          | 10. | 10. Yardy N, Hancox D, Strang TA. A comparison of two airway aids 
            for emergency use by unskilled personnel: the Combitube and laryngeal 
            mask. Anaesthesia 1999;54:181-3 |  | 
         
          | 11. | 11. Grantham H, Phillips G, Gilligan JE. The laryngeal mask in 
            pre-hospital emergency care. Emerg Med 1994;6:193-7 |  | 
         
          | 12. | 12. Berry AM, Brimacombe JR, Verghese C. The laryngeal mask airway 
            in emergency medicine, neonatal resuscitation, and intensive care 
            medicine. Anesthesiol Clin 1998;36:91-109 |  | 
         
          | 13. | Brimacombe J. Emergency airway management in rural practice: use 
            of the laryngeal mask airway. Aust J Rural Health 1995;3:10-19 |  | 
         
          | 14. | Brimacombe J, Berry A, White A. An algorithm for use of the laryngeal 
            mask airway during failed intubation in the patient with a full stomach. 
            Anesth Analg 1993;79:144-63 |  | 
         
          | 15. | Bailey AR, Endotracheal tube DA. The laryngeal mask airway in 
            resuscitation. Resuscitation 1994;28:107-10 |  | 
         
          | 16. | Nolan JP, Parr MJA. Aspects of resuscitation in trauma. Br J Anaesth 
            1997;79:226-40 |  | 
         
          | 17. | Wang TL. Role of laryngeal mask airway in emergency medicine. 
            J Emerg Crit Care Med 2002;13:47-56 |  | 
         
          | 18. | Asai T, Morris S. The laryngeal mask airway: its features, effects 
            and role. Can J Anaesth 1994;41:930-60 |  | 
         
          | 19. | MaCaughey W, Bhanumurthy S. Laryngeal mask placement in the prone 
            position. Anesthesia 1993;48:1104-5 |  | 
         
          | 20. | Stone BJ, Leach AB, Alexander CA, et al. The use of the laryngeal 
            mask airway by nurses during cardiopulmonary resuscitation: results 
            of a multicentre trial. Anesthesia 1994;49:3-7 |  | 
         
          | 21. | Brimacombe JR, Berry A. Mallampati classification and laryngeal 
            mask insertion. Anaesthesia 1993;48:347 |  | 
         
          | 22. | Brimacombe JR, Berry A. Laryngeal mask insertion: a comparison 
            of the standard versus neutral position in normal patients with a 
            view to its use in cervical spine instability. Anaesthesia 1993;48:670-1 |  | 
         
          | 23. | Pennant JH, Pace NA, Gajraj NM. Role of the Laryngeal Mask Airway 
            in the immobile cervical spine. J Clin Anesth 1993;5:226-30. | 
         
          | 24. | Grantham H, Phillips G, Gilligan JE. The laryngeal mask in pre-hospital 
            emergency care. Emerg Med 1994;6:193-7 | 
         
          | 25. | Rabb MF, Minkowitz HS, Hagberg CA. Blind intubation through the 
            laryngeal mask airway for management of the difficult airway in infants. 
            Anesthesiology 1996;84:1510-1 | 
         
          | 26. | Heard CMB, Caldicott LD, Fletcher JE, Selsby DS. Fiberoptic-guided 
            endotracheal intubation via the laryngeal mask airway in pediatric 
            patients: a report of a series of cases. Anesth Analg 1996;82:1287-9 | 
         
          | 27. | Lim SL, Tay DHB, Thomas E. A comparison of three types of tracheal 
            tube for use in laryngeal mask assisted blind orotracheal intubation. 
            Anaesthesia 1994;49:255-7 | 
         
          | 28. | Kadota Y, Oda T, Yoshimura N. Application of a laryngeal mask to 
            a fiberoptic bronchoscope-aided tracheal intubation. J Clin Anesth 
            1992;4:503-4 | 
         
          | 29. | Wafai Y, Knoll W, Salem MR. Facilitation of blind intubation through 
            the Laryngeal Mask Airway. Anesthesiology 1995;83:A19 | 
         
          | 30. | Asai T. Fiberoptic tracheal intubation through the laryngeal mask 
            in an awake patient with cervical spine injury. Anesth Analg 1993;77:404 |  | 
         
          | 31. | Asai T, Latto IP. Use of the lighted stylet for endotracheal intubation 
            via the laryngeal mask airway. Anesth Analg 1998;87:979 |  | 
         
          | 32. | Loken RG, Moir CL. The laryngeal mask airway as an aid to blind 
            orotracheal intubation. Can J Anesth 1992;39:518 |  | 
         
          | 33. | Pennant JH, Joshi GP. Intubation through the Laryngeal Mask Airway. 
            Anesthesiology 1995;83:891-2 |  | 
         
          | 34. | Dingley J, Baynham P, Swart M, Vaughan RS. Ease of insertion of 
            the laryngeal mask airway by inexperienced personnel when using an 
            introducer. Anasethesia 1997;52:756-60 |  | 
         
          | 35. | Brimacombe JR, Berry AM, Brain AIJ. The laryngeal mask airway. 
            Anesth Clin N Am 1995;13:411-37 |  | 
         
          | 36. | Harvey SC. Retrograde intubation through a laryngeal mask airway. 
            Anesthesiology 1996;85:1503-4 |  | 
         
          | 37. | Brain AIJ. An evaluation of the laryngeal mask airway during routine 
            pediatric anaesthesia. Paediatr Anaesth 1995;5:75-6 |  | 
         
          | 38. | Pennant JH, White PF. The laryngeal mask airway: its uses in anesthesiology. 
            Anesthesiology 1993;79:144-63 |  | 
         
          | 39. | Markakis DA, Sayson SC, Schreiner MS. Insertion of the laryngeal 
            mask airway in awake infants with the Robin sequence. Anesth Analg 
            1992;75:822-4 |  | 
         
          | 40. | Paterson SJ, Byrne PJ, Molesky, et al. Neonatal resuscitation using 
            the laryngeal mask airway. Anesthesiology 1994;80:1248-53 |  | 
         
          | 41. | Gerardi MJ, Sacchetti MJ, Cantor RM, et al. Rapid-sequence intubation 
            of the pediatric patient. Ann Emerg Med 1996;28:55-74 |  | 
         
          | 42. | Goldie AS, Hudson I. Fiberoptic tracheal intubation through a 
            modified laryngeal mask. Paediatr Anaesth 1992;2:343-4 |  | 
         
          | 43. | Pearce AW, Heath ML. Aspiration pneumonia and the laryngeal mask 
            airway. Anaesth 1991;46:592 |  | 
         
          | 44. | Wittman PH, Wittman FW. Laryngeal mask and gastric dilation. Anaesthesia 
            1991;46:1085 |  | 
         
          | 45. | Devitt JH, Wenstone R, Noel AG, O’Donnell MP. The laryngeal mask 
            airway and positive-pressure ventilation. Anaesthesiology 1994;80:550-5 |  | 
         
          | 46. | Barker P, Langton JA, Murphy PJ, Rowbotham DJ. Regurgitation of 
            gastric contents during general anesthesia using the laryngeal mask 
            airway. Br J Anaesth 1992;69:314-5 |  | 
         
          | 47. | El Mikatti N, Luthra AD, Healy TEJ, Mortimer AJ. Gastric regurgitation 
            during general anaesthesia in the supine position with the laryngeal 
            and face mask airways. Br J Anaesth 1992;69:529-30 |  | 
         
          | 48. | Brimacombe JR, Berry A. The incidence of aspiration associated 
            with the laryngeal mask airway: a meta-analysis of published literature. 
            J Clin Anesth 1995;7:297-305 |  | 
         
          |  |  |  | 
         
          |  |  |  | 
         
          |  |     |  | 
         
          |  |  |  | 
         
          |  |  |  |